Open call for Proposals

NEW CALL FOR PROPOSALS

SPARK NS Parkinson’s Disease Translational Research Program, 2025 Cohort

SPARK NS is an independent non-profit translational research organization dedicated to efficiently advancing promising neuroscience discoveries from the lab to the clinic.

For the SPARK NS Parkinson’s Disease Translational Research Program, 2025 Cohort, SPARK NS will select academic principal investigators (PIs) with therapeutic discoveries at any stage of development between target identification and entry into clinical trials. For selected projects, SPARK NS will provide funding, education, mentorship, and networking opportunities focused on the translation of promising discoveries to impactful therapeutics.

The duration of the Program is two years. Projects selected will receive milestone-based support of up to $2,000,000 during the two-year program, including discretionary funding for the PI of $50,000 per year1.
1 Not all funds awarded will go to PIs’ laboratories. For example, work to be done by contracted research organizations or academic research facilities will be paid for by SPARK NS directly to the organizations from awarded funds.

Who is Eligible

SPARK NS will accept applications from biomedical research group leaders at academic or nonprofit research institutions in the United States, Canada, the United Kingdom, and Europe with projects at any stage of development between a validated target and entry into clinical trials. We value diversity and are committed to creating an inclusive research environment. Applicants from all backgrounds and experiences are encouraged to apply.

Selection Criteria

Applications are evaluated on the following criteria:

  • Address an unmet clinical need in Parkinson’s disease
  • Use a novel and robust mechanism or approach
  • Have a high probability of success at accomplishing proposed translational objectives
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Call for
Proposals

The Call for Proposals provides detailed information about the process and timeline for applying to the Program.
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Application
Guidelines

The Application Guidelines offers additional information on applying to the Program, including how applications will be evaluated.
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Program
Description

The Program Description and Expectations includes comprehensive information on the Program and what is expected of applicants if selected.
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Application Information

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Call for Proposals

The Call for Proposals document includes comprehensive information on the Program and additional guidance on applying.
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Program Description and Application Guidelines

The Program Description and Application Guidelines document includes comprehensive information on the Program and additional guidance on applying.

Optional Pre-Submission Review

Potential applicants are encouraged but not required to submit a draft topline description (short project summary not to exceed 250 words) and/or graphical abstract for review by June 28, 2024. Within two weeks of submission, applicants will receive feedback on whether their proposal is within the scope of the 2025 SPARK NS Translational Research Program. The pre-submission review is optional and does not impact the overall outcome of the application.
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Application Resources

Link

Background Reading

For background information on the discovery and development of therapeutics and the SPARK model, applicants are encouraged to consult A Practical Guide to Drug Development in Academia when drafting their proposals.

Download

Proposal Template

Applicants should use the Microsoft Word Proposal Template for their proposals to ensure that their proposal meets the formatting requirements.

Download

References Template

Applicants should use the Microsoft Word References Template to ensure that their references included with their application meet the required style.

Learn More

Application Resources

Download

References Template

Applicants should use the Microsoft Word References Template to ensure that their references included with their application meet the required style.

Link

Background Reading

For background information on the discovery and development of therapeutics and the SPARK model, applicants are encouraged to consult A Practical Guide to Drug Development in Academia when drafting their proposals.

Download

Proposal Template

Applicants should use the Microsoft Word Proposal Template for their proposals to ensure that their proposal meets the formatting requirements.

About SPARK NS
SPARK NS is an independent non-profit translational research organization dedicated to efficiently advancing promising neuroscience discoveries from the lab to the clinic.

SPARK NS offers immersive, indication-specific translational research programs for academic principal investigators (PIs) with promising neuroscience discoveries. The programs provide milestone-based funding, education, mentorship, and networking opportunities built on a proven model for collaboration between academic researchers and industry experts. The model has been developed and refined at Stanford University Medical School since 2006. Every aspect of a SPARK NS program is designed to close gaps in knowledge and know-how and eliminate barriers that slow or prevent promising discoveries from directly benefiting patients.
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The Team

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Stephen Kargotich

Executive Director
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Opher Kornfeld

Director, Translational Research & Development
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Marisol Urbano

Director of Programs
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Adriana Garcia

Education Manager
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Charlene Chabata

Project Manager
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Monet Jimenez

Education Curriculum and Content Developer
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Jeyanthi Ramasubbu

Senior Project Manager
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Susan A Thomas

Communications Director
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Daria Mochly-Rosen

Advisor
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Kevin Grimes

Advisor
The Team
The Team

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Contact

1300 El Camino Real
Suite 100
Menlo Park
CA 94025